Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate acute pain and relieve symptoms of arthritis (osteoarthritis
Increased indomethacin dosing for persistent patent ductus arteriosus in preterm infants: a multicenter, randomized, controlled trial
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Indigestion, heartburn, and very occasionally, stomach ulceration and bleeding
This study i
1 Persistent patency of the ductus arteriosus following birth is inversely related to gestational age
, left-to-right shunt large enough to compromise cardiorespiratory status) in premature neonates weighing 500–1750 g when 36–48 hours
Benzodiazepines, even in small doses, significantly reduce dizziness and associated nausea and vomiting
Patients & Methods: This is a multicenter cohort study of 144 preterm infants (22-32 weeks gestational age) at three centers who received at least one treatment course of indomethacin for PDA
Symptomatic patent ductus arteriosus (PDA) is associated with mortality and morbidity in preterm infants
Even though the plasma half-life of indomethacin was variable among premature infants, it was shown to vary inversely with postnatal age and weight
Common side effects of indomethacin are nausea, vomiting, diarrhea, stomach discomfort
Study design: Retrospective
In extremely-low-birth-weight infants, prophylaxis with indomethacin does not improve the rate of survival without neurosensory impairment at 18 months, despite the fact that it reduces the frequency of patent ductus arteriosus and severe periventricular and intraventricular hemorrhage
Both of these drugs are equally Failure of ductus arteriosus closure, termed patent ductus arteriosus (PDA), is primarily an affliction of prematurity, with the ductus remaining open at 7 days of age in up to 64% of infants born at 27 to 28 weeks’ gestation and 87% of infants born at 24 weeks